If you pull the airbox, you "should" add a filter to the crankcase vent(s). In stock form, the breather connects to the "clean" air side of the airbox, which allows it to vent fumes back into the engine, but also ensures only filtered air is drawn back into the engine through the breather.
If you go with POD filters, you no longer have an airbox to vent/supply from. If you leave the vent open, you risk drawing a little unfiltered air back into the engine. Not much, but it is better to have a filter on it.