What day would you like to ride to JR?
About a third of the ride down will be nice, with actually some pleasant riding between Mt. Airy, and Elkins on US 601.
We'd take 614 south from Meadows of Dan, which is 10-15 miles of great road, then make our way to jump in I-77 near Elkins, and ride the interstate the last 35 miles or so.
A breakfast stop could me made on the way, if we start like at 0730.
From JR, we'd have an hour of somewhat boring (not twisty) roads to get back into the hills, and jump on the BRP near Blowing rock.