Fuel blended with Ethanol can bring up some other problems...
The fuel blend can be very sensitive to small amounts of water and high frequency vibrations...the water can cause the ethanol to separate.
I had this very problem on a nice road trip home from Vancouver to Cranbrook, about 900 kms one day. Filled in Vancouver at a site that uses Ethanol blended fuels, on a wet, light rain morning. Once I switched to reserve about 300km later, that was it, lights out.
I had discussions with the station and oil company reps who swore up and down that I had to have had "significant" water in my fuel tank, and that the water and vibration together contributed to the fuel separation.
I have also seen the same problem frequently in Marine applications. In premixed marine service, the water, alcohol and OIL will all separate from the gasoline and drop to the bottom of the fuel tank, leaving your engine to run on insufficient oil.
So...I avoid Ethanol blends in my bikes and boat. It doesn't seem to cause the same level of problems in cars, likely due to the type of vibration.