Ah - near Raystown! I live out East now but grew up in Murrysville which is right along 22 in suburban P'burgh.
As anyone who has read my posts here will attest to, I am not a carb guru. I do imagine that the K&N would make stock settings pretty lean. In particular, the infamous 4K flatspot might go from annoying to nasty or somewhere in between. Maybe up a size or two on the mains and/or add a shim to the needles? A/F screws maybe out a little from their 1.75 stock setting? That's probably where I would start but I've been screwing around with my carbs for a year now and they're still not right so... I'd put it all back together in stock form and see how it runs before messing with it.